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SAN Sesamin: Fat Burning Lignan
What is Sesamin?
Sesamin is a naturally occurring lignan that is present in pure sesame oil. For
your information, a lignan is broadly considered an antioxidant that is present
in unfiltered and unrefined seeds of sesame, pumpkin and flax as well as many
other foods. Besides being a strong antioxidant, sesamin has shown great promise
as a lipid oxidizer as well as to support anti-inflammatory action. Its main
mechanism for fatty acid oxidation (fat burning) is triggered by the enzyme
known as PPAR-alpha. PPAR-alpha (Peroxisome Proliferator-Activator Receptor
Alpha) is documented to exist in muscle, the liver and adipose tissue (fat).
Sesamin being a strong activator of this enzyme (PPAR-alpha) is also involved in
the beta-oxidation of fatty acids while simultaneously decreasing lipogenesis,
or in simple terms, the accretion of new fatty acids. In other words, PPAR-alpha
activation is directly correlated with increasing fat burning in muscle tissue.
Which is a good thing!!!
Sesamin and Insulin Sensitivity
Due to sesamin’s strong beta-oxidizing properties the substance can also affect
leptin levels and is documented to restore insulin sensitivity in obese rodents.
Insulin sensitivity is often impaired in those whose body fat levels exceed 15%
and above. In more simple terms, by providing the necessary substrate; sesamin
is believed to act as a thermostat of sorts that can regulate leptin as well as
insulin levels from within the body keeping both in optimal balance.
Sesamin and Ketosis
Sesamin is a welcomed addition for those who are on ketogenic diets as it is
known to increase ketone production thereby sparing lean muscle tissue that is
otherwise lost through amino acid conversion, usually sacrificed to fuel the
body on low carb diets. Ketogenesis (or the formation of ketones) becomes a
major fuel factor on low carb (Atkins) diets as the brain cannot be driven by
fatty acids and thereby relies on glucose first..and ketones second. So
essentially, without Sesamin in your diet, the body will tap into muscle tissue
for its ketone needs since carbohydrates are obviously kept at bay (at least in
those who are on ketogenic or low carbohydrate diets).
In Closing
Sesamin is an excellent addition to anybody’s workout regimen, not only to
increase fat burning, but also for its overall anti-oxidant and nutrient
partioning properties. Some of the later research even points out that Sesamin
shows great promise in the lowering of LDL (bad) cholesterol while
simultaneously increasing HDL (good) cholesterol levels in humans.
Supplement Facts
Serving Size: 1 Soft Gel
Servings Per Container: 60
Amount Per Serving
Calories 9
Calories from Fat 9
Total Fat 1.0g
Saturated Fat 0.1g
Trans Fat 0g
Cholesterol 0 mg
Ultra Pure Sesame Oil (standardized for 500mg sesamin) 1000mg
Other Ingredients:
Gelatin, Glycerin, Water, FD&C Blue # 1, Titanium Dioxide
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