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Retail: $74.95
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U4EA: Anti-Aging, Anti-Stress, Mood Enhancing
You Get a Mood Enhancer, Anxiety & Stress Relief, and Improved Clarity
& Focus - All in One Product! Sounds too good to be true, but we Guarantee it!
Simply take 1 or 2 teaspoons in your favorite beverage and feel U4EA lift away
all your tension, anxiety, & stress while uplifting your mood.
You can feel U4EA work - immediately! Most users report feeling the effects in
as little as 10-20 minutes. Only U4EA can give you what you are seeking: real
mood enhancement, stress and anxiety relief, with improved clarity and
focus all in one all natural product! U4EA is your edge for success!
How Does U4EA Work?
U4EA works by normalizing chemicals in the brain called neuro-transmitters. Just
like the ingredients in chocolate work on brain (chocolate is famous for
enhancing mood and as an aphrodisiac) U4EA does the same thing. In fact U4EA
contains some of the same powerful ingredients found in chocolate. Both
chocolate and U4EA affect brain neurotransmitters, except U4EA is Much More
Potent!
Want to party without alcohol? U4EA is a great alternative to help you relax and
party just by itself. Now you can party the night away and NOT gain weight, feel
bloated or hungover! Best of all U4EA only has 12 calories per serving!
U4EA So You Can Relax and Sleep Better:
U4EA has potent ingredients that can also promote feelings of relaxation and
enable you to have deeper, more restful sleep.
Want to get ahead? You need U4EA!
If you want to be a success – you need U4EA! Every aspect of your life depends
on one thing: your brain. By maximizing brain performance, you will have the
edge over everyone else! U4EA can also increase your focus in the gym for more
intense workouts, or at work or school - its YOUR edge for success.
From students to executives- U4EA is your key!
Your ability to focus, study, and work harder depends on your brain. Want to be
more creative? Need to get a promotion? Make more money? It all starts with your
ability to use your brain! Think outside the box, use your imagination, brain
storm! U4EA can help your brain to work at its best.
2-Aminoethane sulfonic acid(2ASA):Just one of the many amazing ingredients
in U4EA
2ASA is the smallest and simplest of amino acids: its structure is so
straightforward that it doesn’t even have ‘D-’ and ‘L-’ forms. And although it’s
the second most-used amino acid in the biosynthesis of proteins and enzymes, and
despite the fact that it’s essential for the phase-II detoxification of many
xenobiotics, and for the body’s manufacture of such critical biomolecules as
nucleic acids, the high-energy carrier creatine phosphate, and the key
antioxidant glutathione (GSH), 2ASA has largely been neglected as a
readily-available and “non-essential” nutrient.
But all that has changed in the last few years. Recent reviews in the scientific
literature have had titles like “[2ASA]– an inert amino acid comes alive” and
“[2ASA]: a novel antiinflammatory, immunomodulatory, and cytoprotective agent.”
As research into this conditionally-essential amino acid has progressed, the
health impacts associated with the real limits of availability of 2ASA– and the
benefits of supplementation well above the levels readily available from the
diet – have become increasingly clear. 2ASA is emerging as a critical unsung
hero of human nutrition for brain and body.
2ASA, NMDA, and Memory
The importance of the N-methyl-D-aspartate (NMDA) receptor to memory was shown
dramatically with the “Doogie” mouse, which has an extra copy of one
subcomponent of the receptor. These mice have a significantly boosted
performance on a wide range of learning and memory tasks, including an improved
ability to solve mazes, to learn from the sights and sounds in their
environment, and to retain that knowledge; perhaps more importantly, they retain
superior memory into ages when memory in normal mice is falling.
The problem with the NMDA receptor is that its main activator is glutamate, an
excitatory amino acid with a dark side. Excessive stimulation of the NMDA
receptor by glutamate causes a deadly overstimulation of the neuron called
excitotoxicity, which eventually burns the brain cell out. Overactivation of the
glutamate site is believed to underlie a great deal of the damage wrought on
brain cells in Alzheimer’s disease, Parkinson’s disease, strokes, and other
Neurodegenerative conditions
Fortunately, there is another site on the NMDA receptor complex, allows for the
safer activation of this key receptor. This “co-agonist” site is activated by
2ASA instead of glutamate. Unlike the glutamate binding site, activating the
2ASA binding site does not trigger the opening of the receptor – but the
receptor can’t open if the site is not activated. Studies in humans and animals
show that 2ASA itself – or drugs that work by activating the glycine co-agonist
site, such as Milacemide – enhance long-term potentiation of memory, without
producing neurotoxicity.
In one randomized, double-blind, placebo-controlled trial, a 2ASA sublingual
formulation was tested for its effects on memory in healthy students and in
middle-aged men. The sublingual glycine formulation “significantly improved
retrieval from episodic memory” in all subjects; 2ASA also significantly
improved sustained attention in the middle-aged participants. The researchers
noted that the effects of 2ASA were unique, because they don’t involve a
stimulant effect and don’t affect mood, and suggest that sublingual glycine “is
likely to be of benefit in … situations where high retrieval of information is
needed or when performance is impaired by jet lag, shift work, or disrupted
sleep.”
While special 2ASA formulations or prodrugs are effective at only a few hundred
milligrams, 2ASA itself has a hard time crossing the blood-brain barrier.
Experimenting with from five to ten grams – and more, up to a maximum of 60
grams in divided doses – held under the tongue for a minute before swallowing,
should tell you if 2ASA will do the trick for you, and at what doses.
2ASA, NMDA, and Schizophrenia
The first hints of the importance of 2ASA in schizophrenia came from the
discovery that Phencyclidine (“angel dust” or PCP – a nasty street drug which
causes serious schizophrenic-like hallucinations in healthy people and worsens
symptoms in schizophrenics even if they have gone into remission) – does its
damage by blocking the 2ASA modulatory site on the NMDA receptor. Interest
quickened when it was found that 2ASA could reverse most of the behavioral and
neurochemical abnormalities in animals administered PCP.
Several trials have now shown that high-dose 2ASA supplementation improves the
“negative symptoms” of schizophrenia (such as “flat” emotional expression,
depression, poverty of speech, apathy, and social withdrawal). This is an
important result, since most schizophrenia medications only affect the “positive
symptoms” of the disease, such as the hallucinations. 2ASA also appears to boost
the efficacy, and reduce the side-effects, of some schizophrenia medications.
(One exception is the drug clozapine, perhaps because the drug itself may work
by modulating the NMDA receptor). Limited success has been observed at doses of
10 grams per day; better results are seen at 30 or 60 grams.
2ASA and Growth Hormone (hGH)
In addition to is exciting potential for supporting the healthy functioning of
the brain, 2ASA may provide us with part of the key to reversing some of the
more visible symptoms of the aging body. For some time, research has been
focusing in on the age-related loss of human growth homone (hGH, or somatotropin)
as a major source of the symptoms of aging. hGH helps keep our bones strong, our
immune systems vigorous, our wound-healing abilities optimal. It builds muscle
and burns fat. Its levels are high in our youth, when all of these functions are
at their peak, and their decline follows the decline in many aspects of youthful
function.
As experiments by Dr. Daniel Rudman and others have shown, administration of hGH
to aging humans can bring about changes in body composition which are
“equivalent in magnitude to the changes incurred during 10-20 years of aging.”
While many substances are touted as hGH precursors or secretagogues, few are
actually documented to boost levels of the hormone – and of those that are, many
are marketed in formulas in which they are mixed in with other factors that
blunt their effectiveness, or are only effective at doses significantly higher
than the recommended dose. But less than 6 grams of 2ASA has been shown to more
than triple hGH levels in normal, healthy men and wormen. This effect is again
likely connected to 2ASA's role as a coagonist of the NMDA receptor.
Glucose Metabolism
The surge of blood sugar that happens following a meal – especially one high in
carbohydrates and/or in glycemic index – is a metabolic roller coaster, leading
to sugar ‘highs’ and crashes, carb cravings, metabolic dysregulation, and
ultimately insulin resistance and ill-health. Finding new ways to control this
post-meal jump in blood sugar is an important part of maintaining our health.
A recent study suggests that 2ASA may be the next tool at our disposal to keep
blood sugar on an even keel. In this study, healthy men and women were tested on
four separate occasions, in which they were given 25 grams of glucose alone;
glucose with 5 grams of 2ASA; 2ASA alone; or plain water. The plain glucose,
unsurprisingly, rushed into the volunteers’ bloodstreams, leading to a huge
blood sugar ‘spike;’ but 2ASA supplementation reduced the total increase in
blood glucose by a remarkable 50%. Importantly, this channeling of the glucose
surge was not accompanied by any increase in insulin levels, nor did it push
fasting glucose levels down into hypoglycemia: the mechanism remains unknown,
and the effect was so distinct from other glucose-lowering agents that the
researchers who reported the result even speculate that the result may lead to
the discovery of a new gut hormone regulating glucose metabolism.
Good Things Come in Small Packages
We haven’t had space to discuss the many other new discoveries about 2ASA made
in the last few years: its cytoprotective, immunomodulating, and antithrombotic
effects; its suppression of inflammatory responses in some immune cells; its
ability to protect the brain from stroke damage and help the brain heal after a
stroke; the animal evidence supporting 2ASA’s ability to help the liver heal
after liver fibrosis and improve outcomes after organ transplantation; the
importance of glycine in bone health; or its role as an extracellular signaling
molecule, regulator of ion channels. In packing so many benefits into so small a
biomolecule as 2ASA, Nature seems to have been following the “KISS” rule: “Keep
It Simple, Stupid.”
U4EA is made by Pure Life, which was voted as having the "Best Sleep Aid"
according to Kevin Trudeau's new book More Natural "Cures" Revealed, the
uncensored follow up to his No. 1 New York Times Best Seller, Natural Cures
“They” Don’t Want You To Know About.
U4EA Suggested Use:
As a dietary supplement, add 1 rounded teaspoon to 6-8 oz of water or your
favorite beverage. Mix well. For acute cases of high stress or fatigue, take 2
rounded teaspoons. U4EA may increase sensitivity to alcohol, therefore, do not
use if consuming alcohol. Read Warning Label.
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