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OxyBolin 250: A True Non-steroidal Anabolic Agent Designed To Increase
Muscle Mass And Decrease Bodyfat.
OxyBolin 250 is the product every athlete or health conscious person has been
waiting for. Every now and then, a supplement comes along that defies the odds.
In other words, it actually works the way its advertisers claim, and at the
dosages recommended on the bottle. This is far from the norm, though. In my
opinion, the only clear-cut, non-steroidal anabolic agent and ergogenic aid to
come out of the 90's was creatine. As fate would have it, I recently received a
lot of Soviet translated research on a water soluable, sugar-like derivative of
cholesterol. According to the data, it is orally active, effective at low
dosages (assuming the proper starting material is used prior to extraction),
non-toxic, and in most people, exerts noticeable effects in less than 10 days.
It's called 20-Hydroxyecdysone (20-EC), and I can honestly say that this
compound works, if extracted correctly with the other phytochemicals in
Rhaponticum carthamoides.
As a group, ecdysteroids are naturally occurring, polyhydroxylated plant sterols
that have a plethora of non-hormonal anabolic and ergogenic activities in the
body. Their structure includes three hexane (6 carbon) rings and one pentane (5
carbon) rings. The most biologically active form of the ecdysteroids is thought
to be 20-EC and turkesterone, both of which are harvested from Rhaponticum
carthamoides. Extracts of this potent plant have been approved by the Ministry
of Public Health in the former Soviet Union over 20 years ago to be used for
"raising the mental and physical working ability" as a pharmacological
preparation.
OxyBolin 250 is perfect for:
Anyone who wants to build muscle and/or enhance athletic performance.
Any bodybuilder/ athlete already using anabolic steroids, HGH, and/or
creatine supplements who wants to promote muscle growth.
Anyone who wants a supplement that will complement (rather than be
redundant to) his or her current athletic supplement stack.
Athletes who are avoiding androgen supplements (e.g., women), but still
want to promote muscle growth.
OxyBolin 250 Introduction Rhaponticum carthamoides (Willd.) Iljin, syn. Leuzea
carthamoides (Willd.) DC, is a large perennial herb in the compositae family.
Rhaponticum carthamoides has a wood-like horizontal rhizome, multiple long, hard
roots, and is capable of growing to a height of over six feet. Rhaponticum
carthamoides grows in the pristine alpine and subalpine zones, and alpine
meadows of Southern Siberia. The roots and rhizomes are the medicinal parts,
with the biological activity determined by phytoecdystone quantity, including
ecdysterone.
OxyBolin 250 Chemistry
The principal constituents of the whole plant are ecdysteroids
(5-beta-cholest-6-on-7-ene derivatives) and flavonoids. Also polyacetylenes and
triterpenes have been isolated from different parts of the plant (Girault et.
al. 1984, Szendrei et. al. 1984, Varga et al. 1986 and 1990). Of the isolated
compounds, only 20-hydroxyecdysone and Turkesterone are currently considered to
play an important role in the action of this plant. (Syrov and Kurmukov 1976).
The main flavonoides are 6-methoxy-kampferol, patuletin, isorhamnetin-glycoside
and quercetin-5-glycoside. All leaf and root samples contained
20-hydroxyecdysone as a main compound of Rhaponticum carthamoides. The
20-hydroxyecdysone of the roots ranged from 0.7% to 2.0% being higher than that
of the leaves.
The 20-hydroxyecdysone content of the leaves ranged between 0.006 and 0.10%.
According to the quantitative and qualitative data obtained experimentally, the
optimum time for root harvest of Rhaponticum carthamoides is at the end of
August when the 20-hydroxyecdysone content is the highest.
The research on the effects of Rhaponticum carthamoides has been done for the
last 60 years on the whole plant extract with 20-Hydroxyecdysone and
turkesterone being the principal active compounds. Ingested ecdysteroids survive
exposure to gastric acid and are rapidly absorbed into the enteric blood
vessels. Excretion is primarily via the liver. More recent research has
identified 8 ecdysterones, and has confirmed synergy in their combined usage (Baltaev
and Abubakirov 1987; Gorovits et al 1974; 1977). When using a powdered extract
of Rhaponticum carthamoides ensure that it is standardized to 50-65%
20-Hydroxyecdysterone. This will ensure that the extract possesses an effective
amount of 20-EC and with a natural extraction process it should yield between
75% and 100% total Ecdysones or ecdysteroids. When properly extracted,
Rhaponticum carthamoides should have 2 parts 20-Hydroxyecdysterone to 1 part
total ecdysones or ecdysteroids. Rhaponticum carthamoides contains a number of
other biologically active compounds believed to act in harmony with ecdysterones,
imparting its unique adaptogenic qualities (Azizov and Seifulla 1998). It is
rich in flavanoids, sesquiterpene lactones, and polyines (Opletal et al 1997).
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