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ALRI Chain’D Out 60 Servings Quantity in Basket: None Item: AL26 Retail: $79.99 Price: $39.95 Out of Stock Chain’d Out: Anabolic/Anti-Catabolic BCAA Formula Chain’d Out from ALR Industries sets a standard for optimal performance supplementation. Chain’d Out allows everyone to enjoy supraphysiological and aesthetic results with Non-Hormonal Branch Chain Amino Acids (BCAA’s)! What Are BCAA’s? BCAA’s are the branch chain amino acids leucine, valine and isoleucine. Also note that all amino acids are derived from the assimilation of proteins. BCAA’s are not only 3 of the paramount 18-22 amino acids (as in your body cannot make them and needs them to live), they alone also make up about 70% of your muscle cellular pool and cellular structure. Unfortunately, BCAAs are lost (...muscle loss) at a rapid rate during training and during calorie deficient diets. The result is less muscle and the need to replenish these muscle mainstays…or better yet, trigger an anabolic environment that fosters nutrient super-over-compensation where we need it- for accelerated muscular growth. Why else do we train? The true value of BCAA supplementation is now well established both in literature and in real world application. Anabolic (muscle building) stimuli are their true value rather than wasting good proteins to catabolism (muscle wasting) resulting in more money landing in your toilet. What Does The Research Say? In one excellent study it was shown that, “Branched-chain amino acids activate key enzymes in protein synthesis after physical exercise”. J Nutr. 2006 Jan;136(1 Suppl):269S-73S researchers again validated, “BCAA’s (leucine, isoleucine, and valine), particularly leucine, have anabolic effects on protein metabolism by increasing the rate of protein synthesis and decreasing the rate of protein degradation in resting human muscle.” In another study, we find validation that “Leucine regulates translation initiation of protein synthesis in skeletal muscle after exercise”. J Nutr. 2006 Feb;136(2):533S-537S. Norton LE, Layman DK. Researchers validate the mechanism by which the anabolic signal is initiated: “High-performance physical activity and post-exercise recovery lead to significant changes in amino acid and protein metabolism in skeletal muscle. Central to these changes is an increase in the metabolism of the BCAA leucine. During exercise, muscle protein synthesis decreases together with a net increase in protein degradation and stimulation of BCAA oxidation. BCAA oxidation increases through activation of the branched-chain alpha-keto acid dehydrogenase (BCKDH). BCKDH activity increases with exercise, reducing plasma and intracellular leucine concentrations. After exercise, recovery of muscle protein synthesis requires dietary protein or BCAA to increase tissue levels of leucine in order to release the inhibition of the initiation factor 4 complex through activation of the protein kinase mammalian target of rapamycin (mTOR). Leucine’s effect on mTOR is synergistic with insulin via the phosphoinositol 3-kinase signaling pathway. Together, insulin and leucine allow skeletal muscle to coordinate protein synthesis with physiological state and dietary intake.” A note from Author: One of the two highly respected researchers who penned the peer-reviewed article above is named Layne Norton. To say Layne is brilliant is an understatement. Please take some time to read the complete study if you get a few minutes. It’s worth your time! Did You Know That BCAA’s Could Be Anabolic? BCAA’s can be anabolic if they are correctly structured, protected and delivered right. Never being satisfied with simply good or even just excellent, ALR Industries have taken BCAA’s to the ultimate level for mind-blowing effects. Author L. Rea decided to turn the power way up on the “anabolic drive” with Chain’d Out. First, we utilized esterification technology to increase oral bioavailability 200-300%. Yes, this means way more bang for your buck. Even more important is the fact that our ester-protected BCAA’s in Chain’d Out greatly avoids gluconeogenesis (break-down and conversion to glucose for regular caloric utilization). Why would you pay for a BCAA with half to one third the oral bioavailability and risk the majority of your muscle gains? Why not simply protect yourself from catabolic muscle loss while adding more muscle instead? ALR Industries has taken the science of adaptogens further than anything seen before. Chain’d Out has a rock solid foundation, which is further reinforced by boosting its overall synergy through the addition of potent anti-catabolic agents, anabolic co-factors and last but certainly not least it also promotes mood boosting and energizing effects. Author left no stone unturned in his passion to create the most complete and highest orally bioavailable BCAA formula on the market. Why Settle For Average? Chain’d Out is scientifically engineered to potently thwart muscle breakdown and catabolism. We made it to provide an incredible synergistic boost to the pro-anabolic drive, produce focused energy and mood elevation (without any jitters or negative stimulant qualities), improve strength, endurance, stamina and recovery, create optimized vasodilation and nutrient utilization, enhance oxygenation and fight stress, fatigue as well as other counterproductive body processes. Benefits of Chain’d Out: Provides positive modulation of almost all neurotransmitters (DA, NE, SE, MAOB, Ach, GABA) Enhances energy, focus, mood and stamina Has potent anti-catabolic and anti-cortisol effects Enhances oxygenation and nutrient utilization Provides positive endogenous hormone modulation, including testosterone Has anti-fatigue, anti-stress and anti-oxidant effects Enhances immunity and recovery Supports supraphysiological protein synthesis in muscle tissue Note you will feel the power of this matrix as it is noticeably effective within minutes. Once again ALR Industries has raised the bar in sports supplementation with its formula for Chain’d Out. Chain’d Out sets the standard for non-hormonal performance by creating an anabolic/anti-catabolic environment beyond your wildest expectations! Chain’d Out Supplement Facts: Serving Size: 1 scoop 10.35g Servings Per Container: 60 BCAA Malfactor 211 Matrix 7000mg LeuMal (Leucine Malate) IsoMal (Isoleucine Malate) ValMal (Valine Malate) PerformActiv Propietary Matrix Blend: 1800mg Alanine L-Theanine CordyActiv (Dong Chong Xia Cao) RhoActiv (Rhodiola Rosea Extract) AppleActiv (Apple Peel Extract) Chain’d Out Other Ingredients: Citric Acid, Natural and Artificial Flavors, Aspartame, Acesulfame-K Chain’d Out Suggested Use: As a dietary supplement, mix 1 level scoop (10.35 grams) in 16 ounces of water and shake well. Depending on bodyweight, consume the following serving before and during your workout: For maximum results, you may consume one serving (bodyweight dependent) post-workout. Under 150 lbs.: 1 Scoop 150 - 200 lbs.: 2 Scoops Over 200 lbs.: 3 Scoops Customers who purchased this product, also purchased: Optimum Nutrition 100% Whey Protein - Gold Standard 10 lb $139.99 $76.95 Universal Animal Pak 44 Pak $48.95 $27.95 Beverly International Joint Care 90 Softgels $24.00 $14.95 Scivation Whey Protein 10 lb $119.99 $68.95 Now Foods Cysteine 100 Tablets/500 mg $13.99 $8.00 Optimum Nutrition 100% Whey Protein - Gold Standard 2 lb $31.99 $20.95