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Restore: Male Optimization Matrix
In the ever expanding world of performance and health supplementation today,
there is an assumed division between products considered “hard-core only”, and
those that are intended to promote lean mass acquisition by way of improved
over-all health. Both groups of users actually may have the same
goals…especially men.
Facts…
1) We are performance oriented men and want as much muscle building, sex-driving
testosterone as humanly possible. I mean come on, can you find a guy that says
“I want to be fat and feminine” (okay, one that isn’t looking for a sex-change).
We all want to be healthy optimized males!
2) We don’t want to deal with the negative side affects of excess estrogen from
any source. It shuts down testosterone production and makes people fat and
bitchy. We like being men!
3) We don’t want or need prolactin increases to kill our libido, give us gyno,
or make us want to have a “nesting” moment.
4) If we did want excess estrogen and prolactin, we would be eating
soy-everything and watching day-time drama shows…instead of watching UFC.
5) We hate working our asses off to build lean mass only to have cortisol
production soar from all of training and life’s everyday stresses resulting in
muscle loss and fat deposits around the waist. We worked for the muscle and we
want to keep it.
Estrogens, Prolactin and Cortisol…Oh My!
In today’s “soy-everything/estrogen is good/testosterone is evil” world, men
have to deal with countless phyto and xeno-estrogens in our foods and
environment. Naturally it only gets worse when we realize that these feminizing
phyto and xeno-estrogens are ADDED to our own natural estrogen production in our
bodies. Not bad enough? Okay, then some of us also add products that aromatize
to estrogens.
Yeah, still worse…
Each of these feminizing factors cause a net and additive negative affect upon
our lean mass and other things male…and they add up. The results are 3 fold:
1) Additional fat that produces additional aromatase enzyme resulting in even
more of our manly testosterone being converted into un-manly estrogens. As most
are now aware, aromatase enzyme converts testosterone and other androgens into
estrogens.
2) The increase in estrogens suppresses our male testosterone production system
via inhibition of the the HPTA.
3) Excess estrogen production causes another feminizing hormone to kick in…
Prolactin is a single-chain protein hormone that has serious feminizing
actions (like lactation, increased breast size, HPTA inhibition and suppression
of GH production). There are a few reasons prolactin levels increase, but the
one that is most common and preventable is that when estrogen levels elevate…so
do prolactin levels in males and females alike.
Many are already aware that the first key to optimized testosterone production
is getting rid of excess estrogen in males while stimulating LH production, and
some are even aware that getting prolactin to go away once it starts is not
always simply a matter of getting rid of the estrogen problems. But most are
unaware of how all of this correlates and is compounded by the hormone group
that triggers serious lean tissue loss.
Glucocorticoids are a group of steroids that originate at the adrenal cortex of
the adrenal glands (above your kidneys). The most commonly discussed hormone of
this group is cortisol. When a cortisol molecule meets up with a muscle cell, it
triggers the release of amino acids from the cell. That probably does not sound
like a big deal until you realize that these amino acids come from the breaking
down of the muscle cell proteins. This of course means all of that hard earned
lean mass tissue begins to waste away and become energy or toilet trash.
Cortisol levels are elevated as a result of stress. Unfortunately, the body
views stress stimuli such as increases in muscle tissue mass, training,
sickness, and the spouse in a bad mood as reason to increase circulatory
cortisol levels. Cortisol production can also inhibit endogenous GH and
testosterone production while fueling pathways that allow additional aromatase
enzyme producing fat to accumulate around the waist and upper legs.
So, increases in cortisol production means less muscle, more fat, and
aromatization –>estrogen->prolactin…
and less testosterone production to counter it with. Kind of sucks, huh?
Time to Restore™
ALRI Restore™ is not just another testosterone booster. Though an increase in
testosterone production alone is pretty cool, and one of the reported major
benefits of Restore™, it would be only part of the Restore™ optimized male
matrix. Instead we have opted to see how many arguments we can start (and
knock-offs we can inspire) this time by raising the bar for product expectations
beyond what any one product can currently offer performance oriented males…by
doing the whole job. Its okay, we are men, we like competition!
Estrogen Control
6-Bromodione: There are two types of estrogen aromatase inhibitors and
application of only one leaves the other pathway open for feminizing potential.
1) 6 alpha-Bromodione is a competitive inhibitor of aromatase enzymes. Basically
this means it works by way of binding to the active binding site of the
aromatase enzyme resulting in prevention of interaction with other steroids that
aromatize like testosterone and the rest of our favorite male androgens. This is
great for rapid binding and short term aromatase control, but unfortunately a
competitive inhibitor will eventually let go of the enzyme and allow it to do
feminizing things to manly hormones. So, only half of the job is done, but it
has its important role as well.
2) 6 beta-Bromodione is a mechanism-based irreversible inhibitor of the
aromatase enzyme. An irreversible aromatase inhibitor is also referred to as a
suicide inhibitor. It’s pretty cool in that it acts similar to a competitive
inhibitor in the way it binds, but like a pissed-off ex-girlfriend, it is both
highly selective and it will not let go until death do they part.
Together the two analogs in 6-Bromodione make sure that estrogen is under
control, and many would assume that less estrogen means the prolactin would be
under control as well. Often, once prolactin increases are stimulated, shutting
it back down takes some extra effort and a protracted period of time. How long
are you willing to wait to be an optimized male?
Prolactin Inhibition
Many have heard of or used drugs like bromocriptine that inhibit prolactin
production for medical needs. Of course one of the benefits is an often reported
increase in libido, and “related factors”, but the side-effects such as nausea
and dry mouth can certainly negate the positive.
Prolact-X™ (Chasteberry Diterpine Matrix Extract)
There has been a long history of supplemental use of Chasteberry for treatment
of PMS in women. Most researches believe that PMS is commonly the result of high
prolactin levels so no surprise that we took an interest in this herb.
The amino acid dopamine is the body’s natural controller of prolactin release.
Of course many dopaminergic compounds have been noted as effective treatments
for increasing GH secretion as well, which correlates rather well with
optimization in male performance due to the fact that elevated prolactin results
in decreased GH and IGF-1 production.
The search for the prolactin-suppressive principles in Chasteberry provided a
number of compounds with dopaminergic properties. In short, research showed that
they bound to recombinant dopamine DA2-receptors and suppressed prolactin
release from cultivated lactotrophs as well as in animal experiments. The search
for the chemical identity of the dopaminergic compounds resulted in isolation of
a number of diterpenes of which some clerodadienols were most important for the
prolactin-suppressive effects. They were almost more effective in their
prolactin-suppressive properties than dopamine itself.
Naturally just crushing up a bunch of Chasteberry is not likely to do the job,
but proper preparation of the de-feminizing herb has finally given us an
effective synergist to support male optimization.
So, cool, now that we have dealt with the HPTA suppression and feminizing
issues. By doing so the obvious result is a notable and welcomed increase in
testosterone production. But hey, why not push all the way and reach for
optimization?
Increased Free Testosterone
Free-T™ (Proprietary Pure Avenacosides Matrix)
Seems most males who use supplements for either lean mass gains, libido
augmentation or both have heard of Avena Sativa. Yeah, I know, lots of products
already have some form avena sativa or its extracts in it, so what makes this
one special? Of course we used an extraction process for maximum active compound
content (greatest possible amount of active milligrams per capsule), but in
truth Restore™ as a product is special, our Free-T™ (Proprietary Pure
Avenacosides Matrix) from avena sativa just works well in the whole matrix to
provide maximum results.
In the body testosterone travels around in two forms: Bound or inactive…meaning
it is bound to a protein called SHBGB, and Unbound or free…meaning it is free to
do manly things like build muscle and increase your capacity to perform
sexually.
Basically there are phytochemicals in avena sativa called avenacosides A and B.
Some studies indicate avenacosides increase actual active or free testosterone
in the body by freeing up the bound testosterone from SHBG so there is more
active testosterone. What good is it to have all kinds of extra testosterone if
it is playing S & M games with SHBG?
Cortisol Inhibition
MbAET
Unless you went coma bound in the early 90’s you have been aware of the on going
benefits reaped and progress made with DHEA and its even better metabolites. As
an example are the patented and effective products 7-OXO-DHEA and of course
7-Hydroxy-DHEA analogs. Since these analogs prevent conversion into androgenic
metabolites they have been touted by many as the best thing since pizza.
Considering the lack of androgenic side effects possible while promoting fat
loss, lean mass retention and even maximizing thyroid gland activity, not a real
surprise they have become very popular. Of course oral bioavalability is pretty
poor with most of these analogs thus requiring higher dosages.
Likely the most powerful and effective DHEA analog is b-AET (beta-androstenetriol).
It has been shown in studies to be between 100 and 100,000 times more active
than its DHEA precursor metabolites. However, like most DHEA analogs there is
the issue of poor oral bioavailability. By supporting the delivery value through
simple alkylation, MbAET is nearly 100% orally bioavailable and only takes a few
milligrams to do its job.
Yeah. I know, get to the fat loss and lean muscle side of things in regard to
MbAET…
Glucocorticoids in humans are in two forms. Inactive cortisone and very active
in eating muscle cortisol. There are two enzymes that are able to make each of
these convert into the other.
11b-HSD-1: Converts inactive cortisone into cannibalistic cortisol.
Studies have implicated this event in fat tissue as a pathway for increased fat
storage. Part of the reason GH has a positive affect upon body composition is
through its ability to inhibit 11b-HDS-1
11b-HSD-2: Converts nasty cortisol into cortisone. 11betaHSD2 debulks
intracellular cortisol by 90%. (Let the 11b-HSD-2 rule the house)
Hmmm, so, more 11b-HSD-1 means more cortisol which eats more muscle that
likes to help fat do ugly things.
And less 11b-HSD-1 means…
MbAET inhibits the 11b-HSD-1 enzyme both locally and systemically. This means
that there is less conversion of cortisone to cortisol. Based upon the studies
it appears that in mediating this pathway, it increases immune function and
recovery of cells as well. Less cortisol and fat, more lean muscle and positive
support to health. Not bad!
Optimized Delivery
CYP-X™ (Proprietary Grapefruit Extract)
There were several studies some years back that showed a dramatic increase in
absorption for some compounds when taken with grapefruit juice. The reason was
due to a specific part of grapefruit called dihydoxybergamottin (DHB). It
decreases the gastronomical destruction of compounds susceptible to the CYP-450
enzyme thus allowing a far greater amount of the compound to pass into the
body’s circulatory system instead of the toilet. The components of Restore™
are a good example…
By creating an ultra pure active extract of dihydoxybergamottin (DHB) called CYP-X™
we have maximally increased the overall oral bioavailability of our synergistic
compounds in Restore™ to allow both results and cost effective value in one
product.
Don’t Settle…
Having anything less than optimal testosterone levels is unacceptable for any
male wanting to be the best they can be in all things male, but as a man excess
estrogen and cortisol is a bitch. Restore™ from ALRI is the newest complete
synergistic weapon in the fight against mediocrity for all men.
Restore Suggested Use
Take 1 capsule three times daily with meals. After eight weeks of continuous
use, discontinue for 4 weeks. Do not exceed 8 weeks of continuous use.
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