(Antibiotic) cetirizine HCl - Zyrtec

[hpro]

Would this diminish a PH/PS's gains?

[solomon1979]

Pharmacokinetic interaction studies with cetirizine in adults were conducted with pseudoephedrine, antipyrine, ketoconazole, erythromycin and azithromycin. No interactions were observed. In a multiple dose study of theophylline (400 mg once daily for 3 days) and cetirizine (20 mg once daily for 3 days), a 16% decrease in the clearance of cetirizine was observed. The disposition of theophylline was not altered by concomitant cetirizine administration.

Drug-Drug Interactions: No clinically significant drug interactions have been found with theophylline at a low dose, azithromycin, pseudoephedrine, ketoconazole, or erythromycin. There was a small decrease in the clearance of cetirizine caused by a 400-mg dose of theophylline; it is possible that larger theophylline doses could have a greater effect.

[hpro]

So in english..it won't diminish the PH/PS? Or if it does, it'll only be a slight decrease..?

[solomon1979]

So in english..it won't diminish the PH/PS? Or if it does, it'll only be a slight decrease..?

Basically it would depend on the compound and what it says is that the only thing it was tested against was an anti-histimine and antibiotics.

[FutureKill]

Lol, at first I just glanced at ur avatar hpro and thought it was solomon's. I was wondering why sol was talking to himself :D.

Heh, I don't have any clue about this. I'm just a dummy, but I guess I don't have to actually say that ;)