Difference between L-Citrulline and L-citrulline Malate

[lightiegirl]

Getting confused on which to buy, or is Citrulline Malate, the same thing as L-Citrulline. The powder form of course!

[B-natural]

I believe they are very similar, however I would go with the malate

[wedgylx]

Citrulline Malate has a far better absorbtion rate

[lightiegirl]

Really? I bought the L-citrulline at the store, and a bodybuilder who was freakin' huge, told me the opposite, that the L-citrulline was the purest form.....which is right. I can always return it, just want to make sure I am purchasing the right thing!!

[bigpetefox]

Citrulline is an amino acid with antioxidant properties.. It's main function is the removal of ammonia from skeletal tissues.. It also has an ability to convert to Arginine and prolong the effects of nitric oxide on vasodilation.. The malate form is bonded to malic acid to increase absorbsion.. Free-form Citrulline is just as good, but the effect is dose-dependant.. 3g of the malate form may be the same as 5g of the free-form amino.. ;)

I saw no difference using either at the same doses, it depends on your chemistry so start with a simple amount (2-3g) and increase to where you feel it works similar to the malate form..

[wedgylx]

Citrulline is an amino acid with antioxidant properties.. It's main function is the removal of ammonia from skeletal tissues.. It also has an ability to convert to Arginine and prolong the effects of nitric oxide on vasodilation.. The malate form is bonded to malic acid to increase absorbsion.. Free-form Citrulline is just as good, but the effect is dose-dependant.. 3g of the malate form may be the same as 5g of the free-form amino.. ;)

I saw no difference using either at the same doses, it depends on your chemistry so start with a simple amount (2-3g) and increase to where you feel it works similar to the malate form..

welcome to the board big pete!

[bigpetefox]

Thanks, brother.. Been awhile since I've seen you, good to know there's a good bro on here! :)

[lightiegirl]

Thanks 'BigPete' thats exactly what you told me in the store, but when I looked on line, it said conflicting things!!

[bigpetefox]

Thanks 'BigPete' thats exactly what you told me in the store, but when I looked on line, it said conflicting things!!

What I've also mentioned is that companies will say things to sway you from one to another.. Trust me, try the Citrulline for awhile going up in dose as needed.. I'll personally buy you the malate form if infact it doesn't work how you want it.. I mean, you can find me rather easily.. ;)

Thanks for the huge compliment!

[wedgylx]

Thanks, brother.. Been awhile since I've seen you, good to know there's a good bro on here! :)

I've had a lot of personal stuff going on, so cut down the numbers of boards I moderate/post on due to time restrictions. Are you still in the MA area?

[bigpetefox]

Yup, still in the Ma area for now..

[Trans_Isomer]

L-Citrulline is an amino acid. Citrulline malate is citrulline bound to malic acid, hence citrulline malate. Creatine bound to gluconic acid is creatine gluconate, creatine bound to orotic acid is creatine orotate, and so on.

Citrulline malate has some great studies backing its efficacy

Citrulline/malate promotes aerobic energy production in human exercising muscle.

Bendahan D, Mattei JP, Ghattas B, Confort-Gouny S, Le Guern ME, Cozzone PJ.

Centre de Resonance Magnetique Biologique et Medicale, UMR CNRS 6612, Faculte de Medecine de la Timone, 27 Boulevard Jean Moulin, 13005 Marseille, France.

BACKGROUND: Previous studies have shown an antiasthenic effect of citrulline/malate (CM) but the mechanism of action at the muscular level remains unknown. OBJECTIVE: To investigate the effects of CM supplementation on muscle energetics. METHODS: Eighteen men complaining of fatigue but with no documented disease were included in the study. A rest-exercise (finger flexions)-recovery protocol was performed twice before (D-7 and D0), three times during (D3, D8, D15), and once after (D22) 15 days of oral supplementation with 6 g/day CM. Metabolism of the flexor digitorum superficialis was analysed by (31)P magnetic resonance spectroscopy at 4.7 T. RESULTS: Metabolic variables measured twice before CM ingestion showed no differences, indicating good reproducibility of measurements and no learning effect from repeating the exercise protocol. CM ingestion resulted in a significant reduction in the sensation of fatigue, a 34% increase in the rate of oxidative ATP production during exercise, and a 20% increase in the rate of phosphocreatine recovery after exercise, indicating a larger contribution of oxidative ATP synthesis to energy production. Considering subjects individually and variables characterising aerobic function, extrema were measured after either eight or 15 days of treatment, indicating chronological heterogeneity of treatment induced changes. One way analysis of variance confirmed improved aerobic function, which may be the result of an enhanced malate supply activating ATP production from the tricarboxylic acid cycle through anaplerotic reactions. CONCLUSION: The changes in muscle metabolism produced by CM treatment indicate that CM may promote aerobic energy production.

PMID: 12145119 [PubMed - indexed for MEDLINE]